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After losing their oldest son to ALD, Rosalie Enciñias and Terry Entwald advocate for mandatory newborn genetic sequencing in the United States and battle for a way to save their youngest son. Under a national quarantine, they attend (via computer) a landmark bioethics video conference amongst America’s best and brightest scientific minds. Issues of healthcare, technology, politics, and privilege roar to life as United States health policy is debated and dissected. Inspired by real events.
SYNOPSIS
Synopsis
After losing their oldest son to ALD, Rosalie Enciñias and Terry Entwald advocate for mandatory newborn genetic sequencing in the United States and battle for a way to save their youngest son. Under a national quarantine, they attend (via computer) a landmark bioethics video conference amongst America’s best and brightest scientific minds. Issues of healthcare, technology, politics, and privilege roar to life as United States health policy is debated and dissected.
If you were able to look into your child’s future and foresee any major illness that might befall them, even such late-blooming illnesses as Alzheimer’s and Parkinson’s, with no interventions possible until symptoms become apparent in her late 60s or 70s, would you want to know? What would such knowledge do to you and your family?
What would you do if the secrets of your own DNA were revealed? Would you work to combat any portends of illness, exercising more, eating better, or getting more sleep? Or would anxiety and an insurmountable sense of doom, or even a self-fulfilling prophecy prevail?
The procedures behind the science-fiction of Jurassic Park and Gattaca are within our grasp. What responsibility do we have to that power?
Inspired by real events and cases, Lance Arthur Smith’s Sequence dramatizes these questions and the multi-layered, passionate viewpoints within a crucial bioethics conference; a conference conceived to determine the course of human genomic history. Should all infants in the United States undergo mandatory genetic sequencing? What would you do?
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Characters:
Santiago Entwald-Enciñias – 10-12 range, Latino/mixed ethnicity (*non-speaking role, appears in still and video footage only).
Brandon Entwald-Enciñias – 8-10 range, Latino/mixed ethnicity (*non-speaking role, appears in still and video footage only).
Terry Entwald – Mid-to-late 40s, any ethnicity. Rosalie's husband of 15 years.
Rosalie Enciñias – Early 40s, Latina, high school history teacher, and cross-country coach.
Shelley Landekker – Late 60s, any ethnicity, and one of the country's most respected geneticists. She's been instrumental in nurturing the idea of genome editing, and she executes practical applications across the world.
Abigail (Abby) Stenz – Late 30s/early 40s, any ethnicity. A lawyer specializing in bioethics. She has short hair and speaks with a slight, difficult-to-place accent.
Valverde – Age and ethnicity open, a non-binary transgender co-CEO and Marketing Head of Gene One, a direct-to-consumer genetic testing company. A brilliant writer, they have published articles and short stories in publications both prestigious and grassroots.
Anje Shimura – Late 20s, Japanese-American researcher using stem cells from a patient's own body (induced pluripotent stem cells or iPSCs) to treat Parkinson's. She's also worked with the NIH (National Institutes of Health) on newborn umbilical cord stem cells.
Devin Tasker – Mid-to-late 20s, any ethnicity, Anje's head researcher. He's idiosyncratic and sings movie scores when deep in work. His primary work is with iPSCs, though he worked briefly with Shelley Landekker on CRISPR-Cas9 insertion into wheat to make it bigger and better.
Setting: Early March 2020 through late April 2020. Various homes due to quarantine, via video conference.
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Authorized Materials must be purchased from Stage Rights as a part of your licensing agreement (see Materials).
Billing responsibilities, pertinent copyright information, and playwrights' biographies are available in the show rider that comes with your license agreement.
Authorized Materials must be purchased from Stage Rights as a part of your licensing agreement. Your materials will be sent to you digitally by your Licensing Representative.
The Authorized Materials/Production Package for Sequence are all fulfilled digitally and consist of:
Acting Edition
Stage Manager Script
Available Products
Sequence
by Lance Arthur Smith
PDF Perusal Script of SEQUENCE. Download instantly in the "My Products" or “My Perusals” section of your account. Not intended for production purposes.
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PDF Perusal Script of SEQUENCE. Download instantly in the "My Products" or “My Perusals” section of your account. Not intended for production purposes. |
$7.00 |
